At a glance
Effects
- Muscle hardening / cosmetic dryness: Valued in cutting and contest-prep phases for a hard, dry look rather than large mass gains; produces no estrogenic water retention.[2][3]
- No aromatization to estrogen: As a DHT derivative it cannot be aromatized, so it does not cause estrogenic side effects and may even lower estrogen during a cycle.[1][2]
- Lean recomposition / strength: Marketed as a strength and lean-mass support compound; its anabolic-to-androgenic ratio is roughly 62:25 versus testosterone's 100:100, so it is a relatively mild anabolic.[4]
- Androgenic / masculinizing effects: Can cause acne, increased body/facial hair, voice deepening and increased sexual desire.[1]
Anabolic–androgenic steroid (DHT derivative)
Intramuscular injection
~2.5–3 days (propionate ester)
Schedule III (US controlled substance)
Up to ~24 days in urine
Not 17α-alkylated; no known liver toxicity
About Drostanolone Propionate
Every point here is drawn from public medical and harm-reduction sources. A bracketed number after a claim — like [1]— is a reference: tap it to open the exact source it's based on (numbered list at the bottom). It is not a rating or score. Educational information, not medical advice.
Product specifics
- Est. delivery
- 3–7 business days · EU tracked
Product details as stated by the vendor (claims, not independently verified). Delivery is our standard EU estimate.
What it is
Drostanolone propionate (brand name Masteron) is an injectable anabolic–androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It was once used medically to treat breast cancer in women but is no longer marketed for that purpose, and is now used non-medically for physique and performance enhancement.[1][2]
How it works
Drostanolone propionate is a prodrug that, once injected, is cleaved to active drostanolone, which acts as an agonist of the androgen receptor and triggers genetic changes that increase protein synthesis (anabolism) and decrease amino-acid breakdown (catabolism).[2] Because it is a DHT derivative, it is not a substrate for the aromatase enzyme, so it cannot convert to estrogen — explaining its lack of estrogenic bloat and its mild anti-estrogenic ("hardening") reputation.[2][3] It is a poor substrate for the 3α-HSD enzyme found in muscle, which is thought to give it a higher anabolic-to-androgenic ratio than DHT itself.[3]
Risks & side effects
Most important: The most important risk is cardiovascular. Like other AAS, drostanolone suppresses HDL ("good") cholesterol and raises LDL, and AAS use as a class is linked to high blood pressure, accelerated coronary atherosclerosis, cardiac hypertrophy, thrombosis and an increased risk of heart attack and sudden cardiac death.[5][6] Unlike oral 17α-alkylated steroids, it is not 17α-alkylated and is not known to cause liver toxicity, so the heart and lipids — not the liver — are the main concern.[1]
Common
Serious
Safety & harm reduction
- Women, particularly at moderate-to-high doses, due to the risk of irreversible virilization[4]
- People with existing cardiovascular disease, hypertension, or adverse cholesterol profiles, given AAS cardiovascular toxicity[6][8]
- Anyone with hormone-sensitive conditions or a history where androgen exposure is contraindicated[1]
- Post-cycle therapy (PCT) is needed because, like all AAS, it suppresses natural testosterone production[7]
- For competition testing, longer-estered or this propionate form should be discontinued well before testing as it is detectable for weeks[4][10]
- Conservative dosing, blood-pressure and lipid monitoring, and avoiding stacking reduce cardiovascular risk[5]
Dosage context
A harm-reduction reference guide lists a commonly-reported male bodybuilding dose of roughly 100–150 mg injected every other day, noting these are far higher than any therapeutic dose and that side effects should be expected; community/profile sources cite higher ranges (e.g., 300–600 mg per week).[10][11] These are commonly-reported figures for context only, NOT a prescription or endorsement; sources vary and higher doses mainly increase side effects rather than benefit.[10]
Sources
- 1.Wikipedia — Drostanolone propionate
- 2.DrugBank — Drostanolone (DB00858) / Wikipedia mechanism
- 3.Wikipedia — Drostanolone
- 4.Evolutionary.org — Masteron profile
- 5.American College of Cardiology — Managing CV risk in AAS users
- 6.PMC — Cardiac & metabolic effects of AAS abuse on lipids & BP
- 7.Steroidal.com — Masteron (Drostanolone) profile
- 8.MDPI — Impact of AAS abuse on the cardiovascular system
- 9.INCHEM (PIM 901) — Drostanolone toxicology
- 10.Queensland Insight — Injecting harm-reduction reference guide
- 11.Clinical Schizophrenia — Masteron dosages & side effects
- 12.ScienceDirect — New drostanolone metabolites / detection time
- 13.Cayman Chemical — Drostanolone propionate (Schedule III)
This information is provided for educational and harm-reduction purposes only. It is not medical advice. These substances can carry serious health risks; effects and safe use vary by individual. Consult a qualified healthcare professional before use. Legal status varies by country — it is your responsibility to know your local law. We do not encourage misuse.
Other options for Drostanolone Propionate· 12 offers
Same compound from different labs/brands and pack sizes. Tap a row to switch brand — the price and buy button update instantly.
This compound comes in different forms (e.g. injectable vs oral vs topical). Cost per mg is only comparable within the same form.
| Brand | Form | Strength | Pack | Price | Per mg |
|---|---|---|---|---|---|
Generic | vial | 100 mg/ml | 10 ml | 42,90 € | ★€0.043/mg |
Driada | vial | 100 mg/ml | 10 ml | 57,90 € | €0.058/mg |
Generic | vial | 150 mg/ml | 10 ml | 64,90 € | €0.043/mg |
EVO | vial | 120 mg/ml | 10 ml | 64,90 € | €0.054/mg |
Meta | vial | 100 mg/ml | 10 ml | 84,90 € | €0.085/mg |
Generic | ampoule | 100 mg/ml | 10 ampoule | 104,99 € | — |
Generic | ampoule | 100 mg/ml | 10 ampoule | 113,99 € | ★€0.114/mg |
Generic | vial | 100 mg/ml | 10 ml | 114,99 € | €0.115/mg |
Hemi PharmaSelected | vial | 100 mg/ml | 10 ml | 124,99 € | €0.125/mg |
Intex Pharma | vial | 100 mg/ml | 10 ml | 129,99 € | €0.130/mg |
Generic | — | — | 179,99 € | — | |
Generic | topical-lotion | 100 mg/ml | 100 ml | 279,99 € | €0.028/mg |