At a glance
Effects
- Tissue / tendon repair: Most-promoted use; animal models show accelerated healing of skin, tendon, muscle, ligament and bone, but human efficacy is unproven.[1][2]
- Gastrointestinal protection: Originally described as a cytoprotective anti-ulcer peptide stable in gastric juice; studied in animal models of ulcers and inflammatory bowel disease.[2][5]
- Angiogenesis / vascular effects: Promotes new blood-vessel formation and maintains endothelial integrity in preclinical models via VEGFR2/NO signalling.[5][7]
- Anti-inflammatory: Reported to reduce inflammation in preclinical injury and bowel models.[1][4]
Synthetic pentadecapeptide (15 aa, MW ~1419)
Not FDA-approved; unapproved drug (FDA Category 2)
Prohibited — S0 Non-Approved Substances
Subcutaneous/IM injection or oral
<30 min (animal IV/IM PK; ~15 min IV in rats)
About BPC-157
Every point here is drawn from public medical and harm-reduction sources. A bracketed number after a claim — like [1]— is a reference: tap it to open the exact source it's based on (numbered list at the bottom). It is not a rating or score. Educational information, not medical advice.
Product specifics
- Est. delivery
- 3–7 business days · EU tracked
Product details as stated by the vendor (claims, not independently verified). Delivery is our standard EU estimate.
What it is
BPC-157 (Body Protection Compound 157) is a synthetic 15-amino-acid peptide derived from a protein found in human gastric juice, marketed for injury recovery, tissue/tendon repair, and gut protection.[1][2] It is not approved by any drug regulatory agency for human use and has been studied almost entirely in laboratory animals.[2][3]
How it works
In preclinical (mostly rodent) models, BPC-157 is described as a "cytoprotective" agent that helps maintain blood-vessel (endothelial) integrity and promotes new blood-vessel growth (angiogenesis), which is proposed to underlie its wound- and tissue-healing effects.[5][7] Mechanistically it is reported to act through the VEGF receptor (VEGFR2) and the nitric-oxide (NO) signalling system, and to modulate dopamine, prostaglandin and growth-factor pathways.[4][7] These mechanisms are largely hypothetical in humans: over 80% of published BPC-157 records come from a single research group, experiments typically use only one or two fixed doses, and the same pro-angiogenic/NO activity has been flagged as a plausible tumour-promoting hazard.[6]
Risks & side effects
Most important: Because BPC-157 has barely been studied in humans, no one knows whether there is a safe dose or any safe way to use it.[5] The FDA placed it in its Category 2 of substances presenting significant safety risks, citing potential immune reactions (immunogenicity), peptide-related impurities/contamination, and a lack of human safety data; its pro-angiogenic activity is also a plausible tumour-promoting hazard.[6][8]
Common
Serious
- Immunogenicity — the FDA warns BPC-157 could trigger an immune response.[6]
- Product impurities/contamination — unregulated 'research chemical' products may contain peptide-related impurities or other substances.[6][8]
- Potential tumour promotion — pro-angiogenic (VEGFR2/NO) signalling is a plausible cancer-promoting hazard, and no in-vivo data show it inhibits tumour growth.[6]
Rare
- Unknown long-term and rare effects — long-term impacts have never been characterised in humans, so genuinely rare harms cannot be ruled out.[5]
Safety & harm reduction
- Anyone who is not in a sanctioned clinical trial — it is an unapproved drug with no established safe human dose.[5][6]
- Competitive athletes subject to anti-doping rules — banned at all times under WADA category S0.[3][9]
- People with active or prior cancer should be especially cautious given the theoretical pro-angiogenic tumour-promotion concern.[6]
Dosage context
Commonly-reported, NOT a prescription. Almost all dosing comes from rodent studies (typically ~1–50 µg/kg, often 10 µg/kg, once or twice daily); these do not translate directly to humans.[10][11] Peptide-user communities commonly cluster around 200–500 µg subcutaneously per day, but rigorous human dose-finding data do not exist — a 2025 pilot in just two adults used single IV infusions of 10–20 mg.[11] The elimination half-life is under 30 minutes in animal IV/IM studies (~15 min IV in rats), with IM bioavailability around 14–19% in rats.[12]
Sources
- 1.Wikipedia — BPC-157 (overview, structure, WADA ban)
- 2.PMC — Commentary on BPC-157 as cytoprotectant (origin, gastric juice)
- 3.USADA — BPC-157: Experimental Peptide Creates Risk for Athletes
- 4.Pharmaceuticals 2025 (PMC) — Multifunctionality review (mechanism, ADME)
- 5.PMC — Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
- 6.PMC — Reply to Sikiric et al. (single-source bias, tumour hazard)
- 7.PubMed — Multifunctionality review (VEGFR/NO/dopamine pathways)
- 8.STAT News — BPC-157: big claims and scant evidence (FDA Category 2)
- 9.OPSS (DoD) — BPC-157 prohibited peptide and unapproved drug
- 10.FormBlends — BPC-157 dosage guide (rodent dose ranges)
- 11.thebpc157peptide.com — BPC-157 dosage (community human ranges, pilot study)
- 12.Frontiers in Pharmacology 2022 — BPC-157 pharmacokinetics in rats and dogs
This information is provided for educational and harm-reduction purposes only. It is not medical advice. These substances can carry serious health risks; effects and safe use vary by individual. Consult a qualified healthcare professional before use. Legal status varies by country — it is your responsibility to know your local law. We do not encourage misuse.
Other options for BPC-157· 6 offers
Same compound from different labs/brands and pack sizes. Tap a row to switch brand — the price and buy button update instantly.
This compound comes in different forms (e.g. injectable vs oral vs topical). Cost per mg is only comparable within the same form.
| Brand | Form | Strength | Pack | Price | Per mg |
|---|---|---|---|---|---|
Driada | vial | 10 mg | 1 vial | 64,90 € | — |
Generic | vial | 2 mg | 10 vial | 69,90 € | — |
Generic | — | — | 69,90 € | — | |
Generic | vial | 5 mg | 1 vial | 100,00 € | — |
GenericSelected | vial | 10 mg | 10 vial | 179,99 € | — |
Generic | kit | 5 mg | 10 vial | 550,00 € | — |