At a glance
Effects
- Cognitive / focus support: Marketed and anecdotally reported to support attention, motivation and mental clarity; based on Semax-class research, not confirmed for Adamax in humans[3][7].
- Neuroprotection: Parent peptides show neuroprotective and neurotrophic activity (BDNF/TrkB, reduced oxidative/inflammatory signalling) in preclinical models[5][6].
- Neurogenesis / plasticity: Adamantane neurotrophic peptides (P021) promoted neurogenesis and synaptic plasticity in mice; not demonstrated for Adamax in humans[8].
- Mood / stress resilience: Semax-class peptides are described as neuromodulators affecting stress-response pathways; effects are inconsistent and anecdotal for Adamax[6][7].
Research peptide — Semax (ACTH(4–10)) analogue with adamantane modification
Research use only; not an approved drug or supplement
Intranasal spray or reconstituted subcutaneous (vendor-dependent)
Fast — same-day/30–60 min reported for Semax class
None specific to Adamax; extrapolated from Semax
About Adamax
Every point here is drawn from public medical and harm-reduction sources. A bracketed number after a claim — like [1]— is a reference: tap it to open the exact source it's based on (numbered list at the bottom). It is not a rating or score. Educational information, not medical advice.
Product specifics
- Est. delivery
- 3–7 business days · EU tracked
Product details as stated by the vendor (claims, not independently verified). Delivery is our standard EU estimate.
What it is
Adamax is an experimental research peptide — a modified analogue of the Russian nootropic neuropeptide Semax, itself a synthetic fragment analogue of the hormone ACTH(4–10)[2][5]. It is studied as a neurotrophic/nootropic compound (cognition, neuroprotection, recovery), is sold only as a "research use only" chemical, and is not an approved drug, supplement, or proven performance enhancer[1][4][7].
How it works
Adamax couples an N-acetylated Semax peptide core (Ac-MEHFPGP) to an adamantyl/adamantane group borrowed from the neurotrophic peptide P021; the adamantane modification is intended to increase enzymatic stability, lipophilicity and blood-brain-barrier penetration[2][3]. Its proposed action is borrowed from its parents: Semax raises brain-derived neurotrophic factor (BDNF) and increases TrkB receptor signalling in the hippocampus, supporting synaptic plasticity, while also modulating serotonergic, dopaminergic and cholinergic systems[5][6]. P021 likewise increases BDNF expression (partly by inhibiting LIF signalling) to promote neurogenesis[8]. Crucially, these mechanisms are established for Semax and P021 in animal/cell models — direct mechanistic data on Adamax itself in humans does not exist[1][7].
Risks & side effects
Most important: The single most important thing to know is that Adamax has no established human safety profile — there are no published human clinical trials of Adamax, and what little reassurance exists is extrapolated from its parent compound Semax[7][9]. It is sold strictly as a "research use only" chemical, not for human consumption, so purity, dose and long-term effects are genuinely unknown[1][4].
Common
- Mild nasal irritation, dryness, tingling or burning with intranasal use (reported for the Semax class)[12]
- Headache, especially during the first days or at higher doses[12]
- Restlessness, overstimulation or difficulty relaxing at higher doses[12]
- Anecdotal anxiety or sleep disturbance reported by some users[7]
Serious
Safety & harm reduction
- Anyone seeking an approved/tested therapy — Adamax is an unapproved research chemical not intended for human use[1][4]
- People with diabetes should be cautious: Semax has been linked to raised blood glucose[10]
- People with significant nasal/septum damage if using an intranasal route, or with known peptide allergy[12]
- Pregnancy/breastfeeding and under-18s — no safety data
Dosage context
No validated human dose exists for Adamax. Vendor and "educational" sources report widely inconsistent figures — e.g. roughly 300 mcg–1 mg daily subcutaneously in one protocol, versus "100–200 mg per spray" elsewhere (a ~1000-fold discrepancy that signals unreliable, unverified sourcing)[11][3]. For the parent peptide Semax, human studies have used low-milligram intranasal doses (e.g. ~0.6–1.2 mg/day)[10][12]. Treat all of these as commonly-reported figures, NOT a prescription; the safe dose of Adamax in humans is genuinely unknown.
Sources
- 1.BOC Sciences — Adamax product/structure page
- 2.Nationwide Peptides — Adamax (Ac-MEHFPGP-AG-NH2, Semax+adamantane)
- 3.Steroidwiki — guide on Adamax peptide
- 4.True Lab Peptides — Adamax research-use-only listing
- 5.PubMed — Semax, an ACTH(4-10) analog, regulates BDNF/trkB (Dolotov 2006)
- 6.ScienceDirect — Semax regulates BDNF and trkB in rat hippocampus
- 7.SemaxPolska — Adamax: experimental, no full safety profile
- 8.ScienceDirect — Adamantane neurotrophic peptides / P021 (Li 2010)
- 9.Adamaxpeptide.com — Adamax overview/anecdote
- 10.ADDF/Innerbody — Semax adverse events (nasal discoloration, glucose)
- 11.PeptideDosages.com — Adamax dosing protocol (educational)
- 12.Klear Mind Clinics — Semax side effects (nasal irritation, headache)
- 13.Peptidedosingprotocols — Semax safety/half-life
- 14.Peptide Initiative — P21/P021 BDNF stacking note
This information is provided for educational and harm-reduction purposes only. It is not medical advice. These substances can carry serious health risks; effects and safe use vary by individual. Consult a qualified healthcare professional before use. Legal status varies by country — it is your responsibility to know your local law. We do not encourage misuse.
Other options for Adamax· 2 offers
Same compound from different labs/brands and pack sizes. Tap a row to switch brand — the price and buy button update instantly.
| Brand | Form | Strength | Pack | Price | Per mg |
|---|---|---|---|---|---|
GenericSelected | vial | 5 mg | 10 vial | 209,99 € | — |
Generic | vial | 10 mg | 10 vial | 239,99 € | — |